GRANTS 1、The pre-clinical study of immune characters and special preventive strategies for M.tuberculosis latent infection. National Science and Technology Major Project, 20 350 000 RMB Chief scientist: Sidong Xiong 2、The mechanism study of autoimmune recognition and regulation National Natural Science Foundation of China--Major Program, 10 000 000 RMB Chief scientist: Sidong Xiong 3、The molecular basis and regulation mechanism for the specific recognition of auto antigens and their effects on auto immune response Major State Basic Research Development Program of China (973 Program), 6 500 000 RMB Program P.I.: Sidong Xiong 4、Pharmaceutical development center based on immune microenvironment National Science and Technology Major Project, 4 160 000 RMB Program P.I: Yunsen Li 5、The basic study of vaccines and adjuvants for persistent infection Major State Basic Research Development Program of China (973 Program), 1 730 000 RMB Section P.I.: Chunsheng Dong 6、Study on autoreactive immune responses in RA Major State Basic Research Development Program of China (973 Program), 3 250 000 RMB Program P. I.: Xiaoming Gao 7、The generation and functions of regulatory antibodies in autoimmune recognition and regulation National Natural Science Foundation of China--Major Program, 3 000 000 RMB Program P. I.: Xiaoming Gao 8 The immune regulatory role of IL-1a in liver chronic inflammation and tumor development National Natural Science Foundation of China, 550 000 RMB P. I.: Haiyan Liu 9、The evasion of the host innate immune signaling pathway by human herpes viral deubiquitinase (DUB) National Natural Science Foundation of China, 1 000 000 RMB P. I.: Chunfu Zheng 10,Roles of Calreticulin in immunoregulation and tumor surveillance National Natural Science Foundation of China, 900 000 RMB P. I.: Xiaoming Gao 11、Ubiquitination of IFNs activated antiviral protein Viperin and its effect on aniviral function of IFNs National Natural Science Foundation of China, 900 000 RMB P. I.: Hui Zheng 12、Role of membrane-bound lactoferrin in B-cell functions and the associated molecular mechanisms National Natural Science Foundation of China, 800 000 RMB P. I.: Jun Wang 13、The role and molecular mechanism of HMGB1 in ER stress-associated inflammation in viral mvocarditis National Natural Science Foundation of China, 800 000 RMB Investigator: Yan Yue 14、The generation and functional study of ALD-DNA induced SLE animal model National Natural Science Foundation of China, 1 300 000 RMB P. I.: Sidong Xiong 15、Crosstalk between hemidesmosomes and actin cytoskeleton in the epidermis National Natural Science Foundation of China, 850 000 RMB P. I.: Huimin Zhang 16、Molecular mechanism of chitosan on intestinal CD11b+ DC enhanced B cell secretion of specificity sIgA National Natural Science Foundation of China, 800 000 RMB P. I.: Wei Xu 17、The function and mechanism of Cbl-b/C-Cbl in inhibiting the development of CD8+ DC National Natural Science Foundation of China, 800 000 RMB P. I.: Jinping Zhang 18、Vector and pathogens: Tick innate immune signaling pathway and their roles in anti-bacterial infection National Natural Science Foundation of China, 700 000 RMB P. I.: Jianfeng Dai 19、The molecular study of CVB3 viral-like particle assembly National Natural Science Foundation of China, 700 000 RMB P. I.: Chunsheng Dong 20、The GVL effect of donor NK cells and IL-15 in allogeneic hematopoietic stem cell transplantation National Natural Science Foundation of China, 600 000 RMB P. I.: Haiyan Liu 21、The role of a novel mucosal delivery system targeting to M cell National Natural Science Foundation of China, 600 000 RMB Investigator: Yan Yue 22,Screening of HSV-1proteins interacting with important innate immunity signaling molecules by reverse two-hybrid system, and investigation of the molecular mechanisms through which they interfere with innate immunity. National Natural Science Foundation of China, 580 000 RMB P. I.: Chunfu Zheng 23、Study on novel immune receptors specific for glycans National Natural Science Foundation of China, 350 000 RMB P. I.: Xiaoming Gao 24、The role of donor NK cells and IL-15 in the promotion of engraftment during nonmyeloablative allo-HSCT National Natural Science Foundation of China, 350 000 RMB P. I.: Haiyan Liu 25、The gender different MCP1/IKK signaling in myocardial macrophages from CVB3 induced viral myocarditis mice National Natural Science Foundation of China, 340 000 RMB P. I.: Sidong Xiong 26、Mechanism of innate immune molecule TREM2 inherent identification, the response and the negative control of Mycobacterium tuberculosis National Natural Science Foundation of China, 300 000 RMB P. I.: Wei Xu 27、Molecular mechanism of the synergistic effects if apolipoprotein E4 ans Herpes Simplex Virus Type 1 infection in Alzheimer’s Disease.National Natural Science Foundation of China National Natural Science Foundation of China, 280 000 RMB Investigator: Jie Li 28、Membrane bound lactoferrin function as a new pattern recognization receptor National Natural Science Foundation of China, 230 000 RMB Investigator: Hongliang Dong 29、Role and mechanism for DDX25 promoting Dengue virus infection National Natural Science Foundation of China, 230 000 RMB Investigator: Tingting Feng 30、Function and mechanism of mir-184 in recurrent spontaneous abortion National Natural Science Foundation of China, 230 000 RMB Investigator: Fulu Dong 31、MMP3 activates NFkB in nucleus: the novel anti-Dengue virus function of MMP3 National Natural Science Foundation of China, 250 000 RMB P. I.: Jianfeng Dai 32、Studies on biochemical and functional properties of soluble calreticulin in serum % synovial fluid of patients with rheumatoid arthritis National Natural Science Foundation of China, 250 000 RMB Investigator: Fangyuan Gong 33、Role of ZBTB24 in adaptive immunity and the underlying mechanisms National Natural Science Foundation of China, 200 000 RMB P. I.: Jun Wang 34、mir-29b2 regulates the T1/T2 B cell development. National Natural Science Foundation of China, 200 000 RMB Investigator: Fei Xia 35、The effect of the novelIL-15 isoform during the autoimmune disease National Natural Science Foundation of China, 230 000 RMB Investigator: Bo Hu 36、Recombinant calreticulin activates regulatory B cells and it’s underlying mechanisms. National Natural Science Foundation of China, 230 000 RMB P. I.: Chao Hong 37、The identification and characterization of cellular factor related to HIV-1 pre integration complex National Natural Science Foundation of China, 220 000 RMB P. I.: Chunsheng Dong 38,Characterization of antagonizing mechanism of innate immunity by Varicella-Zoster Virus immediate-early protein ORF61. National Natural Science Foundation of China, 220 000 RMB Investigator: Shuai Wang 39、Study on linear ion trap MS methods for identification of tumor-associated glycospingolipids National Natural Science Foundation of China, 200 000 RMB P. I.: Yunsen Li 40、The endoplasmic reticulum stress in viral myocarditis: role and mechanism study Ph.D. Programs Foundation of Ministry of Education of China，120 000 RMB P. I.: Sidong Xiong 41、Structure basis responsible for the immune recognition of oligosaccharide Ph.D. Programs Foundation of Ministry of Education of China，120 000 RMB P. I.: Xiaoming Gao 42、The role of donor NK cells in the promotion of engraftment during allogeneic bone marrow transplantation Ph.D. Programs Foundation of Ministry of Education of China，60 000 RMB P. I.: Haiyan Liu 43、Establishment and application of a new method for treatment of tuberculosis. Ph.D. Programs Foundation of Ministry of Education of China，40 000 RMB Investigator: Xingmei Qi 44、Membrane-bound lactoferrin functions as a new mitogen receptor on B cells Ph.D. Programs Foundation of Ministry of Education of China，40 000 RMB Investigator: Hongliang Dong 45、The generation and application of a novel CPE30-DNA-Chitosan delivery system targeting to M cell Ph.D. Programs Foundation of Ministry of Education of China，40 000 RMB Investigator: Yan Yue 46、Generation and functional study of coxsackievirus B3 virus-like particle in viral myocarditis. Overseas returnee research fund of Ministry of Education of China，30 000 RMB P. I.: Chunsheng Dong 47、Role and mechanism for DDX25 promoting Dengue virus infection National Science Foundation for Post-doctoral Scientistsof China，50 000 RMB Investigator: Tingting Feng 48、The roles of protein ubiquitination and deubiquitination in IFNs induced antiviral signaling. JiangSu Province Natual Science Fund for Distinguished Young Scholars，1 000 000 RMB P. I.: Hui Zheng 49、The pathogenesis and preventive strategies study for viral induced myocarditis JiangSu Province Natual Science Foundation Inovation Project, 1 000 000 RMB P. I.: Sidong Xiong 50、Identification and analysis of oligosaccharide immune receptors JiangSu Province“333”project, 250 000 RMB P. I.: Xiaoming Gao 51、The innate recognition of DNA and its role in the pathogenesis of SLE JiangSu Province“333”project, 200 000 RMB P. I.: Sidong Xiong 52、LPS promote the proliferation and polarization of MDSC by up-regulating the expression of Let-7e JiangSu Province Natual Science Foundation, Major program, 150 000 RMB P. I.: Jinping Zhang 53、Study on novel immune receptors for beta-glucans Natural Science Foundation of the Jiangsu Higher Education Institutions, 150 000 RMB P.I.: Xiaoming Gao 54、The innate recognition and anti viral mechanism of TRIM22 to Hepatitis B virus JiangSu Province Natual Science Foundation, Major program, 300 000 RMB P. I.: Sidong Xiong 55、Tick innate immune signaling and tick-borne-bacterial infection Jiang Su Province Natural Science Foundation, 200 000 RMB P.I.: Jianfeng Dai 56、The role of mir-29b2 in regulating T1/T2 B cell development Jiang Su Province Natural Science Foundation, 100 000 RMB P.I.: Jinping Zhang 57、Identification of glycophingolipids involved in hepatoma metastasis JiangSu Province Science and Technology program, 80 000 RMB P. I.: Yunsen Li 58、Screening of the Host Proteins Interacting with HSV-1 ICP22, and characterization of their Biological functions during Infecton. Natural Science Foundation of the Jiangsu Higher Education Institutions, 32 000 RMB Investigator: Shuai Wang 59、The role and mechanism study of HMGB1 inendoplasmic reticulum stress with viral induced myocarditis Natural Science Foundation of the Jiangsu Higher Education Institutions, 30 000 RMB Investigator: Yan Yue 60、Immunostimulating effect of calreticulin in sera of rheumatoid arthritis patients and the associated molecular mechanisms. Natural Science Foundation of the Jiangsu Higher Education Institutions, 30 000 RMB Investigator: Fangyuan Gong 61、Role of recombinant calreticulin in inhibiting mouse experimental autoimmune encephalomyelitis JiangSu Province Natual Science Foundation, 30 000 RMB P.I.: Chao Hong 62、Development of a novel oral tumor vaccine using Salmonella as a minigene autotransporter carrier Development Program of Suzhou Administration of Science and technology, 150 000 RMB P. I.: Haiyan Liu |