Principal Investigator 
Xiaoming Gao MD, Ph.D. Professor of IBMS Professor XiaoMing Gao received his Bachelor’s degree in Peking University Medical Centerin 1984 and Ph.D. degree in Wellcome Research Laboratories in the United Kingdom. He performed his post-doc training in Andrew McMichael’s lab at University of Oxford. Because of his significant contributions to the studies of Infectious and autoimmune diseases, he became the first Chinese ever received full financial support by the Wellcome Trust as a senior scientist. Professor Gao organized his own research team in 1994, at the Imperial College of Science, Technology and Medicine in London. His studies were focused on the pathogenesis and treament of autoimmune diseases. At 1997, professor Gao was recruited by Peking University Health Science Center.and served as the director of the Department of Immunology. His research was then expanded to include the mechanisms of immune regulation and immune responses in Severe Acute Respiratory Syndromes. His major academic accomplishments include more than 50 SCI papers with over 800 citations, He also wrote or directed the publication of 12 textbooks in immunology. Professor Gao is currently Dean of the School of Basic Sciences, SooChow University, Co-Director of the Institute of Biology and Medical Sciences, and Associate Dean of SooChow University Medical center.
Research Interest
Immunological Function of Calreticulin Glycoimmunobiology
Selected publications:
Dai Hui, Dong HL, Sun SL, Liu XJ, Su J, Li ZG, Gao XM. Disease association and arthritogenic potential of circulating antibodies against the polygalacturonic acid (PGA) moiety. J Autoimmun. Under review. Dong HL, Dai Hui, Hu XM, Xiong SD, Gao XM. The(1→6)-β-glucan moiety represents a cross-reactive epitope of infection-induced malignancy surveillance. J Immunol. 2014. 192:1302-1312 . Zhang T, Xia Y, Zhang L, Bao W, Hong C, Gao XM. CD1d(hi)CD5 (+) B cells differentiate into antibody-secreting cellsunder the stimulation with calreticulin fragment. Protein Cell. 2013 Nov;4(11): 872-81. Hong C, Zhang T, Gao XM. Recombinant murine calreticulin fragment 39-272 expands CD1d(hi)CD5+ IL-10-secreting B cells that modulate experimental autoimmune encephalomyelitis in C57BL/6 mice. Mol Immunol. 2013 Oct; 55(3): 237-46. Huang SH, Zhao LX, Hong C, Duo CC, Guo BN, Zhang LJ, Gong Z, Xiong SD, Gong FY, Gao XM. Self-oligomerization is essential for enhanced immunological activities of soluble recombinant calreticulin. PLoSOne. 2013 Jun 10;8(6):e64951. Li WJ, Long K, Dong HL, Gao XM. Adjuvanticity of a recombinant calreticulin fragment in assisting anti-β-glucanIgG responses in T cell-deficient mice. Clin Vaccine Immunol. 2013 Apr; 20(4):582-9. Qiu X, Hong C, Zhong Z, Li Y, Zhang T, Bao W, Xiong S, Gao XM. Modulation of cellular immunity by antibodies against calreticulin. Eur J Immunol. 2012 Sep; 42(9): 2419-30. Qiu X, Hong C, Li Y, Bao W, Gao XM. Calreticulinas a hydrophilic chimeric molecular adjuvant enhances IgG responses to the spike protein of severe acute respiratory syndrome coronavirus. Microbiol Immunol. 2012 Aug; 56(8): 554-61. Dai H, Han XQ, Gong FY, Dong H, Tu PF, Gao XM. Structure elucidation and immunological function analysis of a novel b-glucan fromthe fruit bodies of Ployrus umbellatus (Pers.) Fries. Glycobiol. 2012 June 18. Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, Liu X, Sun L, Lv P, and Gao XM. Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol.2010.185:4561-4569. Teammembers 
E-mail：xmgao@suda.edu.cn Office：Dushu Lake 703-B320 Office Tel：(86)512 658 82613
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