2021

210.Y.F. Zhang, S.J. Yue, H.L. Sun*, R. Haag, Z.Y. Zhong*, An intelligent cell-selective polymersome-DM1 nanotoxin toward triple negative breast cancer, J. Control. Release 2021, 340, 331-341.210.pdf

209.Z.H. Zhu, M.R. Wu, J. Sun, Z.Y Huangfu, L.L. Yin, W.P. Yong, J. Sun, G.L. Wang*, F.H. Meng, Z.Y. Zhong*, Redox-sensitive iodinated polymersomes carrying histone deacetylase inhibitor as a dual-functional nano-radiosensitizer for enhanced radiotherapy of breast cancer, Drug Deliv. 2021, 28, 2301-2309.209.pdf

208.J.J. Wei, Y.F. Xia, F.H. Meng*, D.W. Ni, X.Y. Qiu, Z.Y. Zhong*, Small, Smart, and LDLR-Specific Micelles Augment Sorafenib Therapy of Glioblastoma, Biomacromolecules 2021, 22, 4814-4822.208.pdf

207Z.Q. Zhang, Q. Zhang, J.G. Xie, Z.Y. Zhong*, C. Deng*, Enzyme-responsive micellar JQ1 induces enhanced BET proteins inhibition and immunotherapy of malignant tumor, Biomater. Sci. 2021, 9, 6915-6926.207.pdf

206N. Yu, Y.F. Zhang, J.Y. Li, W.X. Gu, S.J. Yue, B. Li, F.H. Meng, H.L. Sun*, R. Haag, J.D. Yuan, and Z.Y. Zhong*, Daratumumab Immunopolymersome-Enabled Safe and CD38-Targeted Chemotherapy and Depletion of Multiple Myeloma, Adv. Mater. 2021, 2007787.206.pdf

205Z. Wang, F.H. Meng, and Z.Y. Zhong*, Emerging targeted drug delivery strategies toward ovarian cancer, Adv. Drug Deliv. Rev. 2021, 113969.205.pdf

204S.P. Cao,Y.F. Xia,J.X. Shao,B.B. Guo,Y.Y. Dong,I.A. B. Pijpers, Z.Y. Zhong, F.H. Meng*, L.K.E.A. Abdelmohsen, D.S. Williams*, and J. C.M. van Hest*, Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy, Angew. Chem. Int. Ed. 2021, 60, 17629-17637.204.pdf

203Y.H. Wei, Y.P. Sun, J.J. Wei, X.Y. Qiu, F.H. Meng*, G. Storm*, J.D. Yuan, Z.Y. Zhong*, Selective transferrin coating as a facile strategy to fabricate BBB-permeable and targeted vesicles for potent RNAi therapy of brain metastatic breast cancer in vivo, J. Control. Release 2021, 337, 521-529.203.pdf

202W.X. Gu, R.B. Qu, F.H. Meng*,J.L.M. Cornelissen*, and Z.Y. Zhong*, Polymeric Nanomedicines Targeting Hematological Malignancies, J. Control. Release 2021, 337, 571-588.202.pdf

201Y.F. Xia, J.J. Wei, S.S. Zhao, B.B. Guo, F.H. Meng*, B. Klumperman, and Z.Y. Zhong*, Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma, J. Control. Release 2021, 336, 262-273.201.pdf

200J. Ouyang, Y. Jiang, C. Deng, Z.Y. Zhong*, and Q. Lan*, Doxorubicin Delivered via ApoE-Directed Reduction-Sensitive Polymersomes Potently Inhibit Orthotopic Human Glioblastoma Xenografts in Nude Mice, Int. J. Nanomed. 2021, 16, 4105-4115.200.pdf

199Z.Y. Zhong*, Controlled delivery systems are the cornerstone of advanced therapies and vaccines: An Asian perspective, J. Control. Release 2021, 334, 34-3.199.pdf

198Z. Wang, S.S. Zhao, W.X. Gu, Y.Y. Dong, F.H. Meng*, J.D. Yuan, and Z.Y. Zhong*,α3 integrin-binding peptide-functionalized polymersomes loaded with volasertib for dually-targeted molecular therapy for ovarian cancer, Acta Biomaterialia 2021, 124, 348-357. 198.pdf

197Q.Y. Fan, Y.Y. Liu, G.H. Cui, Z.Y. Zhong*, and C. Deng*, Brain delivery of Plk1 inhibitor via chimaeric polypeptide polymersomes for safe and superb treatment of orthotopic glioblastoma, J. Control. Release2021, 329, 1139-1149.197.pdf

196W.X. Gu, T.H. Liu, D.Y. Fan, J.B. Zhang, Y.F. Xia, F.H. Meng*, Y. Xu*, J.L.M. Cornelissen, Z.J. Liu, and Z.Y. Zhong*, A6 peptide-tagged, ultra-small and reduction-sensitive polymersomal vincristine sulfate asa smart and specific treatment for CD44+ acute myeloid leukemia, J. Control. Release 2021, 329, 706-716.196.pdf

195W.X. Gu, F.H. Meng*, R. Haag, and Z.Y. Zhong*, Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation, J. Control. Release 2021, 329, 676-695.195.pdf

194J. Zhang, X.X. Wang, L. Cheng*, J.D. Yuan and Z.Y. Zhong*, SP94 Peptide Mediating Highly Specific and Efficacious Delivery of Polymersomal Doxorubicin Hydrochloride to Hepatocellular Carcinoma in Vivo, Colloids Surf. B: Biointerfaces 2021, 197, 111399.194.pdf