一、2023-至今发表的SCI论文(*通讯作者)

1.Jin E, Wang S, Chen D, Wang JP, Zeng Y, Sun R*,ZhangHT*. (2024) P4HA2 activates mTOR via hydroxylation and targeting P4HA2-mTOR inhibits lung adenocarcinoma cell growth.Oncogene,43(24):1813-1823.https://doi.org/10.1038/s41388-024-03032-1

2.Wang Z, Lei Z, Wang Y, Wang S, Wang JP, Jin E, Liu X, Sun R*,ZhangHT*. (2024) Bone-metastatic lung adenocarcinoma cells bearing CD74-ROS1 fusion interact with macrophages to promote their dissemination.Oncogene,43(28):2215-2227.https://doi.org/10.1038/s41388-024-03072-7

二、2013-2022年间发表的SCI论文(*通讯作者)

1.Su Z, Sun Z, Wang Z, Wang S, Wang Y, Jin E, Li C, Zhao J, Liu Z, Zhou Z, Wang Y, Chen X, Liu X, Lei Z*,ZhangHT*.(2022) TIF1γinhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.Cell Reports,41(3):111513.(Research Article)https://doi.org/10.1016/j.celrep.2022.111513

2.Wang S, Sun Z, Lei Z*,ZhangHT*. (2022) RNA-binding proteins and cancer metastasis.Semin Cancer Biol,86(Pt 2):748-768. (Invited Review, IF:17.012)https://doi.org/10.1016/j.semcancer.2022.03.018

3.Sun Z, Su Z, Zhou Z, Wang S, Wang Z, Tong X, Li C, Wang Y, Chen X, Lei Z,Zhang HT*. (2022) RNA demethylase ALKBH5 inhibits TGF-β-induced EMT by regulating TGF-β/SMAD signaling in non-small cell lung cancer.FASEB J,36(5):e22283.(Research Article)https://doi.org/10.1096/fj.202200005RR

4.Wang S, Tong X, Li C, Jin E, Su Z, Sun Z, Zhang W, Lei Z,Zhang HT*. (2021) Quaking 5 suppresses TGF-β-induced EMT and cell invasion in lung adenocarcinoma.EMBO Reports,22(6):e52079.(Research Article)https://doi.org/10.15252/embr.202052079

5.Tong X, Wang S, Lei Z, Li C, Zhang C, Su Z, Liu X, Zhao J,Zhang HT*. (2020) MYOCD and SMAD3/SMAD4 form a positive feedback loop and drive TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer.Oncogene,39(14):2890-2904.https://doi.org/10.1038/s41388-020-1189-4

6.Wang L, Tong X, Zhou Z, Wang S, Lei Z, Zhang T, Liu Z, Zeng Y, Li C, Zhao J, Su Z, Zhang C, Liu X, Xu G*,Zhang HT*. (2018) Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γin non-small cell lung cancer.Mol Cancer,17(1):140 (p1-18).(Research Article)https://doi.org/10.1186/s12943-018-0889-7

7.Li C, Wan L, Liu Z, Xu G, Wang S, Su Z, Zhang Y, Zhang C, Liu X, Lei Z*,Zhang HT*. (2018) Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer.Cancer Lett,418:185-195.https://doi.org/10.1016/j.canlet.2018.01.036

8.Wang L, Yang H, Lei Z, Zhao J, Chen Y, Chen P, Li C, Zeng Y, Liu Z, Liu X,Zhang HT*. (2016) Repression of TIF1γby SOX2 promotes TGF-β-induced epithelial-mesenchymal transition in non-small-cell lung cancer.Oncogene,35(7):867-877.https://doi.org/10.1038/onc.2015.141

9.Shi X, Zhan L, Xiao C, Lei Z, Yang H, Wang L, Zhao J,Zhang HT*.(2015) miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer.Oncotarget,6(22):19043-19054.https://doi.org/10.18632/oncotarget.4232

10.Lei Z, Xu G, Wang L, Yang H, Liu X, Zhao J,Zhang HT*.(2014) MiR-142-3p represses TGF-β-induced growth inhibition through repression of TGFβR1 in non-small cell lung cancer.FASEB J,28(6):2696-2704.https://doi.org/10.1096/fj.13-247288

11.Chen H, Yang T, Lei Z, Wang L, Yang H, Tong X, Yang WT, Zhao J, Gu Y, Chen Y*,Zhang HT*.(2015) RNF111/Arkadia is regulated by DNA methylation and affects TGF-β/Smad signaling associated invasion in NSCLC cells.Lung Cancer,90(1):32-40.https://doi.org/10.1016/j.lungcan.2015.07.010

12.Yang H, Wang L, Zhao J, Chen Y, Lei Z, Liu X, Xia W, Guo L,Zhang HT*.(2015) TGF-β-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer.Lung Cancer,87(3):249-257.https://doi.org/10.1016/j.lungcan.2014.12.015

13.Hu H, Xu Z, Li C, Xu C, Lei Z,Zhang HT*, Zhao J*.(2016) MiR-145 and miR-203 represses TGF-β-induced epithelial-mesenchymal transition and invasion by inhibiting SMAD3 in non-small cell lung cancer cells.Lung Cancer,97:87-94.https://doi.org/10.1016/j.lungcan.2016.04.017

14.Liu RY, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J*,Zhang HT*.(2014) JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells.Int J Oncol,44(5):1643-1651.https://doi.org/10.3892/ijo.2014.2310

15.Qian Q, Shi X, Lei Z, Zhan L, Liu RY, Zhao J, Yang B, Liu Z,Zhang HT*.(2014) Methylated +58CpG site decreases DCN mRNA expression and enhances TGF-β/Smad signaling in NSCLC cells with high metastatic potential.Int J Oncol,44(3):874-882.https://doi.org/10.3892/ijo.2014.2255

16.Chen J, Liu RY, Yang L, Zhao J, Zhao X, Lu D, Yi N, Han B, Chen XF, Zhang K, He J, Lei Z, Zhou Y, Pasche B*, Li X*,Zhang HT*.(2013) A two-SNP IL-6 promoter haplotype is associated with increased lung cancer risk.J Cancer Res Clin Oncol,139(2):231-242.https://doi.org/10.1007/s00432-012-1314-z

17.Liu XL, Xue BX, Lei Z, Yang DR, Zhang QC, Shan YX*,Zhang HT*.(2013) TGFBR3 co-downregulated with GATA3 is associated with methylation of the GATA3 gene in bladder urothelial carcinoma.Anat Rec (Hoboken),296(11):1717-1723.https://doi.org/10.1002/ar.22802

18.Ling N, Gu J, Lei Z, Li M, Zhao J,Zhang HT*, Li X*.(2013) microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma.Oncol Rep,30(5):2111-2118.https://doi.org/10.3892/or.2013.2685

19.Liu XL, Xiao K, Xue B, Yang D, Lei Z, Shan Y*,Zhang HT*.(2013) Dual role of TGFBR3 in bladder cancer.Oncol Rep,30(3):1301-1308.https://doi.org/10.3892/or.2013.2599

20.Huang H, Sun P, Lei Z, Li M, Wang Y,Zhang HT*, Liu J*.(2015) miR-145 inhibits invasion and metastasis by directly targeting Smad3 in nasopharyngeal cancer.Tumor Biol,36(6):4123-4131.https://doi.org/10.1007/s13277-015-3046-6

21.Xiao K, Yu Z, Shi DT, Lei Z, Chen H, Cao J, Tian W, Chen W*,Zhang HT*.(2015) Inactivation of BLU is associated with methylation of Sp1-binding site of BLU promoter in gastric cancer.Int J Oncol,47(2):621-631.https://doi.org/10.3892/ijo.2015.3032

三、2003-2012年间发表的SCI论文 (* 通讯作者)

1.Liu RY, Song X, Chen P, Lei Z, Miao J, Yi N, Zhang K, Pasche B*,Zhang HT*.(2012) Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals.Exp Ther Med,3(4):655-664.https://doi.org/10.3892/etm.2012.454

2.Lu F,Zhang HT*.(2011) DNA methylation and nonsmall cell lung cancer.Anat Rec (Hoboken),294(11):1787-1795.https://doi.org/10.1002/ar.21471

3.Sun J, Lei Z, Liu RY, Lu Y, Zhuang Z, Jiang X, Qian Q, Liu Z, Zhao J*,Zhang HT*.(2011) A haplotype of TGFBR1 is predominantly found in non-small cell lung cancer patients displaying TGFBR1 allelic-specific expression.Oncol Rep,25(3):685-691.https://doi.org/10.3892/or.2011.1135

4.Liu Z, Li W, Lei Z, Zhao J, Chen XF, Liu R, Peng X, Wu ZH, Chen J, Liu H, Zhou QH*,Zhang HT*.(2010) CpG island methylator phenotype involving chromosome 3p confers an increased risk of non-small cell lung cancer.J Thorac Oncol,5(6):790-797.https://doi.org/10.1097/jto.0b013e3181d862f5

5.Liu RY, Lei Z, Li W, Xu L, Liu Z, Chen XF, Zhao J*,Zhang HT*.(2009) Infrequently methylated event at sites -181 to -9 within the 5' CpG island of E-cadherin in non-small cell lung cancer.Exp Lung Res,35(7):541-553.https://doi.org/10.1080/01902140902770016

6.Lei Z, Liu RY, Zhao J, Liu Z, Jiang X, You W, Chen XF, Liu X, Zhang K, Pasche B*,Zhang HT*.(2009) TGFBR1 haplotypes and risk of non-small-cell lung cancer.Cancer Res,69(17):7046-7052. (Highlighted article)https://doi.org/10.1158/0008-5472.CAN-08-4602

7.Valle L, Serena-Acedo T, Liyanarachchi S, Hampel H, Comeras I, Li Z, Zeng Q,Zhang HT, Pennison MJ, Sadim M, Pasche B*, Tanner SM*, de la Chapelle A*. (2008) Germline Allele-specific Expression of TGFBR1 Confers an Increased Risk of Colorectal Cancer.Science,321 (5894):1361-1365.https://doi.org/10.1126/science.1159397

8.Liu Z, Zhao J, Chen XF, Li W, Liu R, Lei Z, Liu X, Peng X, Xu K, Chen J, Liu H, Zhou QH*,Zhang HT*.(2008) CpG island methylator phenotype involving tumor suppressor genes located on chromosome 3p in non-small cell lung cancer.Lung Cancer,62(1):15-22.https://doi.org/10.1016/j.lungcan.2008.02.005

9.Zhao J, Liu Z, Li W, Liu X, Chen XF,Zhang HT*.(2008) Infrequently methylated event at sites -362 to -142 in the promoter of TGFβR1 gene in non-small cell lung cancer.J Cancer Res Clin Oncol,134(8):919-925.https://doi.org/10.1007/s00432-008-0392-4

10.You W, Liu Z, Zhao J, Zheng M, Zheng SY, Liu X,Zhang HT*.(2007) No association between TGFBR1*6A and lung cancer.JThorac Oncol,2(7):657-659.https://doi.org/10.1097/JTO.0b013e318070ccd7

11.Zhang HT*, Zhao J, Zheng SY, Chen XF. (2005) Is TGFBR1*6A really associated with increased risk of cancer?J Clin Oncol,23(30):7743-7744.https://doi.org/10.1200/JCO.2005.02.9108

12.Zhang HT*.(2005) Int7G24A variant of the TGFBR1 gene and cancer risk: a meta-analysis of three case-control studies.Lung Cancer,49(3):419-420.https://doi.org/10.1016/j.lungcan.2005.03.038

13.Chen XF,Zhang HT*, Qi QY, Sun MM, Tao LY. (2005) Expression of E-cadherin and nm23 is associated with the clinicopathological factors of human non-small cell lung cancer in China.Lung Cancer,48(1):69-76.https://doi.org/10.1016/j.lungcan.2004.09.009

14.Zhang HT, Chen XF, Wang MH, Wang JC, Qi QY, Zhang RM, Xu WQ, Fei QY, Wang F, Cheng QQ, Chen F, Zhu CS, Tao SH, Luo Z*. (2004) Defective expression of transforming growth factor β receptor type II is associated with CpG methylated promoter in primary non-small cell lung cancer.Clin Cancer Res,10(7):2359-2367.https://doi.org/10.1158/1078-0432.ccr-0959-3

15.Zhang HT, Fei QY, Chen F, Qi QY, Zou W, Wang JC, Zhang RM, Tao SH, Chen XF, Luo ZW*. (2003) Mutational analysis of the transforming growth factor beta receptor type I gene in primary non-small cell lung cancer.Lung Cancer,40(3):281-287.https://doi.org/10.1016/S0169-5002(03)00121-1