刘阳教授课题组在Microchimica Acta上发表论文

题目：

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

作者：

Manman Yang Weiqian Kong Hao Li Juan Liu Hui Huang Yang Liu Zhenhui Kang

单位：

Jiangsu Key Laboratory for Carbon-Based Functional Materials &

Devices, Institute of Functional Nano & Soft Materials (FUNSOM),

Soochow University, 199 Ren’ai Road, Suzhou 215123, Jiangsu,

People’s Republic of China

摘要：

We describe the preparation of carbon dots (CDs) from glucose that possess high stability, a quantum yield of 0.32, and low toxicity (according to an MTT assay). They were used, in combination with the fluorogenic zinc(II) probe quercetin to establish a fluorescence resonance energy transfer (FRET) system for the determination of Zn(II). The CDs are acting as the donor, and the quercetin-Zn(II) complex as the acceptor. This is possible because of the strong overlap between the fluorescence spectrum of CDs and the absorption spectrum of the complex. The method enables Zn(II) to be determined in the 2 to 100 μM concentration range, with a 2 μM detection limit. The method was applied to image the distribution of Zn(II) ions in HeLa cells.

影响因子：

3.741

分区情况：

3区

链接：

http://link.springer.com/article/10.1007/s00604-015-1592-7